Publications

2014年

Sukegawa S, Sakuma R, Ohmine S, Takeuchi H, Ikeda Y and Yamaoka S.: Suppressor of Cytokine Signaling 1 Counteracts Rhesus Macaque TRIM5α-Induced Inhibition of Human Immunodeficiency Virus Type-1 Production. PLoS One. 9(10):e109640 2014.

Barnor J, Yamamoto N, Brandful J, Ampofo W, Bonney K, Bonney E, Odoom K, Aidoo, S, Alale M, Ntim NA, Amoah YO, Ofori SB, Ndzinu J, Addo NA, Nyarko A, Ido E, Ishikawa K, Yamaoka S.: Establishment of in-house quantitative real-time RT-PCR assay for HIV-1 viral load measurement and its application to evaluate efficacy of ART in Ghanaian patients in an urban setting. Journal of AIDS and Clinical Research, in press 2014.

Tung NH, Suzuki M, Uto T, Morinaga O, Kwofie KD, Ammah N, Koram KA, Aboagye F, Edoh D, Yamashita T, Yamaguchi Y, Setsu T, Yamaoka S, Ohta N, Shoyama Y. : Anti-Trypanosomal Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica. Am J Chin Med. 1:(1)-16, 2014. 

Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, Inazawa J, Yuasa Y, Kubota T, Yamaoka S. NF-κB Inducing Kinase, a Central Signaling Component of the Non-Canonical Pathway of NF-κB, Contributes to Ovarian Cancer Progression. PLoS One, 9(2):e88347, 2014.

2013年

Ido E, Yamaoka S.:Two research projects on infectious diseases conducted in Noguchi Memorial Institute for Medical Research, University of Ghana by Tokyo Medical and Dental University. Uirusu 63(1):79-86. 2013.

Sugiyama R, Abe M, Nishitsuji H, Murakami Y, Takeuchi H and Takaku H. : Induction of heat-shock protein 70 by prostaglandin A1 inhibits HIV-1 Vif-mediated degradation of APOBEC3G. Antiviral Research 99(3):307-11. 2013.

Muramatsu S, Tanaka S, Mogushi K, Adikrisna R, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Nakayama K, Tanaka H, Yamaoka S. : Arii S.Visualization of stem cell features in human hepatocellular carcinoma reveals in vivo significance of tumor-host interaction and clinical course. Hepatology 58(1):218-28. 2013.

Hori T, Takeuchi H, Saito H, Sakuma R, Inagaki Y, Yamaoka S.: A carboxy-terminally truncated human CPSF6 lacking residues encoded by exon 6 inhibits HIV-1 cDNA synthesis and promotes capsid disassembly. J Virol. 87(13):7726-36. 2013.

Lee H, Komano J, Saitoh Y, Yamaoka S, Kozaki T, Misawa T, Takahama M, Satoh T, Takeuchi O, Yamamoto N, Matsuura Y, Saitoh T, Akira S.: Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus. Natl Acad Sci U.S.A. 23;110(30):12379-84. 2013.

Nii-Trebi NI, Ibe S, Barnor JS, Ishikawa K, Brandful JA, Ofori SB, Yamaoka S, Ampofo WK, Sugiura W. : HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana. PLoS One. 19;8(8):e71972. 2013.

2012年

Ozono E, Komori H, Iwanaga R, Tanaka T, Sakae T, Kitamura H, Yamaoka S, Ohtani K. Tumor suppressor TAp73 gene specifically responds to deregulated E2F activity in human normal fibroblasts. Genes Cells. 8:660-72. 2012

Uota S, Zahidunnabi Dewan M, Saitoh Y, Muto S, Itai A, Utsunomiya A, Watanabe T, Yamamoto N, Yamaoka S. An IκB kinase 2 inhibitor IMD-0354 suppresses the survival of adult T-cell leukemia cells. Cancer Sci. 1:100-6. 2012

Saitoh T, Komano J, Saitoh Y, Misawa T, Takahama M, Kozaki T, Uehata T, Iwasaki H, Omori H, Yamaoka S, Yamamoto N, Akira S. Neutrophil extracellular traps mediate a host defense response to human immunodeficiency virus-1. Cell Host Microbe 12:109-16 2012

Adikrisna R, Tanaka S, Muramatsu S, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Yamaoka S, Arii S. Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents. Gastroenterology. 143:234-45 2012

Sakuma R, Takeuchi H*§. SIV replication in human cells. Frontiers in Microbiology. 3:162. 2012

Takeuchi H*§, Ishii H, Kuwano T, Inagaki N, Akari H, Matano T. Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication. Retrovirology, 9(1):3. 2012 (* Main contribution § Corresponding author)

Matsunaga S, Sawasaki T, Ode H, Morishita R, Furukawa A, Sakuma R, Sugiura W, Sato H, Katahira M, Takaori-Kondo A, Yamamoto N, Ryo A. Molecular and enzymatic characterization of XMRV protease by a cell-free proteolytic analysis. J Proteomics. 75(15):4863-73. 2012

Ido E, Karhemere S, Taty-Taty R, Tada T, Yasunaga M, Iwamoto S, Umehara A, Parra HJ, Kashonguwe Z, Muyembe JJ Molecular epidemiology of HIV in the Congo Basin-From the generation site of AIDS virus. J International Health, 27(3):284 2012

2011年

Kondo S, Wakisaka N, Muramatsu M, Zen Y, Endo K, Murono S, Sugimoto H, Yamaoka S, Pagano JS, Yoshizaki T.: Epstein-Barr virus latent membrane protein 1 induces cancer stem/progenitor-like cells in nasopharyngeal epithelial cell lines. J Virol. 85(21):11255-64. 2011.

Refaat A, Zhou Y, Suzuki S, Takasaki I, Koizumi K, Yamaoka S, Tabuchi Y, Saiki I, Sakurai H.: Distinct Roles of Transforming Growth Factor-{beta}-activated Kinase 1 (TAK1)-c-Rel and Interferon Regulatory Factor 4 (IRF4) Pathways in Human T Cell Lymphotropic Virus 1-transformed T helper 17 Cells Producing Interleukin-9. J Biol Chem. 17;286(24):21092-9. 2011.

Zhang J, Yamada O, Kida S, Matsushita Y, Yamaoka S, Chagan-Yasutan H, Hattori T.: Identification of CD44 as a downstream target of noncanonical NF-κB pathway activated by human T-cell leukemia virus type 1-encoded Tax protein. Virology. 413(2):244-52, 2011.

Furuta RA, Miyazawa T, Sugiyama T, Kuratsune H, Ikeda Y, Sato E, Misawa N, Nakatomi Y, Sakuma R, Yasui K, Yamaguti K, Hirayama F.: No association of xenotropic murine leukemia virus-related virus with prostate cancer or chronic fatigue syndrome in Japan. Retrovirology. 17;8:20. 2011.

Ohmine S, Sakuma R, Sakuma T, Thatava T, Takeuchi H, Ikeda Y.: The antiviral spectra of TRIM5α orthologues and human TRIM family proteins against lentiviral production. PLoS One. 14;6(1):e16121. 2011.

Sakuma R and Takeuchi H§. Retroviral Host Cell Factors:APOBEC3G, TRIM5, and Cyclophilins. HIV and AIDS - Updates on Biology, Immunology, Epidemiology and Treatment Strategies ISBN 978-953-307-665-2:183-196. 2011.

Ndembi N, Iwamoto S, Ngansop C, Lemey P, Abimiku A, Mbanya D, Kaptue L, Ido E: High frequency of HIV-1 dual infections in Cameroon, West Central Africa. J Acquir Immune Defic Syndr, 57(2), e25-e27, 2011.

2010年

Masuda M, Maruyama T, Ohta T, Ito A, Hayashi T, Tsukasaki K, Kamihira S, Yamaoka S, Hoshino H, Yoshida T, Watanabe T, Stanbridge EJ, *Murakami Y. : CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I (HTLV-I) transformed cells and adult T-cell leukemia (ATL) cells: possible involvement of CADM1 in pathogenesis of ATL. J.Biol. Chem. 285: 15511-15522, 2010

Saitoh, Y., Marti'nez Bruyn, V.J., Uota, S., Hasegawa, A., Yamamoto, N., Imoto, I., Inazawa, J. and *Yamaoka, S.: Overexpression of NF-kB Inducing Kinase Underlies Constitutive NF-kB Activation in Lung Cancer Cells. Lung Cancer. 70: 263-270, 2010

Suzuki S, Zhou Y, Refaat A, Takasaki I, Koizumi K, Yamaoka S, Tabuchi Y, Saiki I, Sakurai H: Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways. J Biol Chem. 285 :4441-4446, 2010

Sakuma R, Ohmine S, Ikeda Y: Determinants for the rhesus monkey TRIM5alpha-mediated block of the late phase of HIV-1 replication. J Biol Chem. 285:3784-3793, 2010

Ohmine S, Sakuma R, Sakuma T, Thatava T, Solis GP, Ikeda Y: Cytoplasmic body component TRIM5{alpha} requires lipid-enriched microdomains for efficient HIV-1 restriction. J Biol Chem. 285-34508-34517, 2010

 

2009年

Miyakawa K, Ryo A, Murakami T, Ohba K, Yamaoka S, Fukuda M, Guatelli J, Yamamoto N : BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction. PLoS Pathog. 12:e1000700, 2009

Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, Akira S, Takao T, Tanaka K, Iwai K: Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol. 11:123-132, 2009

Nonaka M, Uota S, Saitoh Y, Takahashi M, Sugimoto H, Amet T, Arai A, Miura O, Yamamoto N, Yamaoka S: Role for protein geranylgeranylation in adult T-cell leukemia cell survival. Exp Cell Res. 315: 141-150, 2009

Sakuma R, Sakuma T, Ohmine S, Silverman RH, Ikeda Y: Xenotropic murine leukemia virus-related virus is susceptible to AZT. Virology. 397:1-6, 2009

 

2008年

Mitsuki Y, Ohnishi K, Takagi H, Oshima M, Yamamoto T, Mizukoshi F, Terahara K, Kobayashi K, Yamamoto N, Yamaoka S, Yokota T.: A single amino acid substitution in the S1 and S2 Spike protein domains determines the neutralization escape phenotype of SARS-CoV. Microbes Infect. 10 (8):908-15. 2008.

Feng WY, Tanaka R, Inagaki Y, Saitoh Y, Chang MO, Amet T, Yamamoto N, Yamaoka S, Yoshinaka Y.: Pycnogenol, a procyanidin-rich extract from French maritime pine, inhibits intracellular replication of HIV-1 as well as its binding to host cells. Jpn J Infect Dis. 61(4):279-85. 2008.

Zhang J, Yamada O, Kawagishi K, Araki H, Yamaoka S, Hattori T, Shimotohno K: Virology.Human T-cell leukemia virus type 1 Tax modulates interferon-alpha signal transduction through competitive usage of the coactivator CBP/p300. 30; 379(2):306-13. 2008.

Nonaka M, Uota S, Saitoh Y, Takahashi M, Sugimoto H, Amet T, Arai A, Miura O, Yamamoto N, Yamaoka S.: Role for protein geranylgeranylation in adult T-cell leukemia cell survival. Exp Cell Res. 15; 315(2):141-50. 2008.

Saitoh, Y., N. Yamamoto, M. Z. Dewan, H. Sugimoto, V. J. Martinez Bruyn, Y. Iwasaki, K. Matsubara, X. Qi, T. Saitoh, I. Imoto, J. Inazawa, A. Utsunomiya, T. Watanabe, T. Masuda and S. Yamaoka: Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood. 111:5118-5129, 2008.

Kobayashi, S., A. Wada, S. Shibasaki, M. Annaka, H. Higuchi, K. Adachi, N. Mori, T. Ishikawa, Y. Masuda, H. Watanabe, N. Yamamoto, S. Yamaoka and T. Inamatsu: Spread of a large plasmid carrying the cpe gene and the tcp locus amongst Clostridium perfringens isolates from nosocomial outbreaks and sporadic cases of gastroenteritis in a geriatric hospital. Epidemiol Infect. 1-6, 2008.

Amet, T., M. Nonaka, M. Z. Dewan, Y. Saitoh, X. Qi, S. Ichinose, N. Yamamoto and S. Yamaoka: Statin-induced inhibition of HIV-1 release from latently infected U1 cells reveals a critical role for protein prenylation in HIV-1 replication. Microbes Infect. 10:471-480, 2008.

 

2007年

Suganami, T., K. Tanimoto-Koyama, J. Nishida, M. Itoh, X. Yuan, S. Mizuarai, H. Kotani, S. Yamaoka, K. Miyake, S. Aoe, Y. Kamei and Y. Ogawa: Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages. Arterioscler Thromb Vasc Biol. 27:84-91, 2007.

Qi, X., Y. Koya, T. Saitoh, Y. Saitoh, S. Shimizu, K. Ohba, N. Yamamoto and S. Yamaoka: Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: involvement of NF-kappaB activation. Virology. 361:325-334, 2007.

Nonaka, M., S. Yamaoka and N. Yamamoto: [Aberrant NF-kappaB2/p52 generation in Hodgkin lymphoma cells]. Nippon Rinsho. 65 Suppl 1:198-201, 2007.

Fontan, E., F. Traincard, S. G. Levy, S. Yamaoka, M. Veron and F. Agou: NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex. FEBS J. 274:2540-2551, 2007.

 

2006年

Yamamoto, M., T. Okamoto, K. Takeda, S. Sato, H. Sanjo, S. Uematsu, T. Saitoh, N. Yamamoto, H. Sakurai, K. J. Ishii, S. Yamaoka, T. Kawai, Y. Matsuura, O. Takeuchi and S. Akira: Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat Immunol. 7:962-970, 2006.

Saitoh, T., A. Tun-Kyi, A. Ryo, M. Yamamoto, G. Finn, T. Fujita, S. Akira, N. Yamamoto, K. P. Lu and S. Yamaoka: Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol. 7:598-605, 2006.

Hai, T., M. L. Yeung, T. G. Wood, Y. Wei, S. Yamaoka, Z. Gatalica, K. T. Jeang and A. R. Brasier: An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation. J Virol. 80:4227-4241, 2006.

 

2005年

Sakai, H., A. Jinawath, S. Yamaoka and Y. Yuasa: Upregulation of MUC6 mucin gene expression by NFkappaB and Sp factors. Biochem Biophys Res Commun. 333:1254-1260, 2005.

Saitoh, T., M. Yamamoto, M. Miyagishi, K. Taira, M. Nakanishi, T. Fujita, S. Akira, N. Yamamoto and S. Yamaoka: A20 is a negative regulator of IFN regulatory factor 3 signaling. J Immunol. 174:1507-1512, 2005.

Nonaka, M., R. Horie, K. Itoh, T. Watanabe, N. Yamamoto and S. Yamaoka: Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts. Oncogene. 24:3976-3986, 2005.

Miura, H., M. Maeda, N. Yamamoto and S. Yamaoka: Distinct IkappaB kinase regulation in adult T cell leukemia and HTLV-I-transformed cells. Exp Cell Res. 308:29-40, 2005.

 

2004年

Yamamoto, M., S. Yamazaki, S. Uematsu, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Kuwata, O. Takeuchi, K. Takeshige, T. Saitoh, S. Yamaoka, N. Yamamoto, S. Yamamoto, T. Muta, K. Takeda and S. Akira: Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. Nature. 430:218-222, 2004.

Nitta, T., A. Chiba, N. Yamamoto and S. Yamaoka: Lack of cytotoxic property in a variant of Epstein-Barr virus latent membrane protein-1 isolated from nasopharyngeal carcinoma. Cell Signal. 16:1071-1081, 2004.

Hironaka, N., K. Mochida, N. Mori, M. Maeda, N. Yamamoto and S. Yamaoka: Tax-independent constitutive IkappaB kinase activation in adult T-cell leukemia cells. Neoplasia. 6:266-278, 2004.

Dewan, M. Z., M. Watanabe, K. Terashima, M. Aoki, T. Sata, M. Honda, M. Ito, S. Yamaoka, T. Watanabe, R. Horie and N. Yamamoto: Prompt tumor formation and maintenance of constitutive NF-kappaB activity of multiple myeloma cells in NOD/SCID/gammacnull mice. Cancer Sci. 95:564-568, 2004.

Agou, F., F. Traincard, E. Vinolo, G. Courtois, S. Yamaoka, A. Israel and M. Veron: The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains. J Biol Chem. 279:27861-27869, 2004.

 

2003年

Saitoh, T., M. Nakayama, H. Nakano, H. Yagita, N. Yamamoto and S. Yamaoka: TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. J Biol Chem. 278:36005-36012, 2003.

Saito, N., G. Courtois, A. Chiba, N. Yamamoto, T. Nitta, N. Hironaka, M. Rowe and S. Yamaoka: Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell lines. J Biol Chem. 278:46565-46575, 2003.

Ryo, A., F. Suizu, Y. Yoshida, K. Perrem, Y. C. Liou, G. Wulf, R. Rottapel, S. Yamaoka and K. P. Lu: Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol Cell. 12:1413-1426, 2003.

Nitta, T., A. Chiba, A. Yamashita, M. Rowe, A. Israel, M. Reth, N. Yamamoto and S. Yamaoka: NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus. Cell Signal. 15:423-433, 2003.

Courtois, G., A. Smahi, J. Reichenbach, R. Doffinger, C. Cancrini, M. Bonnet, A. Puel, C. Chable-Bessia, S. Yamaoka, J. Feinberg, S. Dupuis-Girod, C. Bodemer, S. Livadiotti, F. Novelli, P. Rossi, A. Fischer, A. Israel, A. Munnich, F. Le Deist and J. L. Casanova: A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency. J Clin Invest. 112:1108-1115, 2003.

 

2002年

Saitoh, T., H. Nakano, N. Yamamoto and S. Yamaoka: Lymphotoxin-beta receptor mediates NEMO-independent NF-kappaB activation. FEBS Lett. 532:45-51, 2002.

Muto, A., J. Ruland, L. M. McAllister-Lucas, P. C. Lucas, S. Yamaoka, F. F. Chen, A. Lin, T. W. Mak, G. Nunez and N. Inohara: Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-kappa B activation induced by phorbol ester. J Biol Chem. 277:31871-31876, 2002.

Jono, H., T. Shuto, H. Xu, H. Kai, D. J. Lim, J. R. Gum, Jr., Y. S. Kim, S. Yamaoka, X. H. Feng and J. D. Li: Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription. J Biol Chem. 277:45547-45557, 2002.

Chinanonwait, N., H. Miura, N. Yamamoto and S. Yamaoka: A recessive mutant cell line with a constitutive IkappaB kinase activity. FEBS Lett. 531:553-560, 2002.

Agou, F., F. Ye, S. Goffinont, G. Courtois, S. Yamaoka, A. Israel and M. Veron: NEMO trimerizes through its coiled-coil C-terminal domain. J Biol Chem. 277:17464-17475, 2002.

 

2001年

Tada, K., T. Okazaki, S. Sakon, T. Kobarai, K. Kurosawa, S. Yamaoka, H. Hashimoto, T. W. Mak, H. Yagita, K. Okumura, W. C. Yeh and H. Nakano: Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death. J Biol Chem. 276:36530-36534, 2001.

Purcell, N. H., C. Yu, D. He, J. Xiang, N. Paran, J. A. DiDonato, S. Yamaoka, Y. Shaul and A. Lin: Activation of NF-kappaB by hepatitis B virus X protein through an IkappaB kinase-independent mechanism. Am J Physiol Gastrointest Liver Physiol. 280:G669-677, 2001.

Ogura, Y., N. Inohara, A. Benito, F. F. Chen, S. Yamaoka and G. Nunez: Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem. 276:4812-4818, 2001.

Nicot, C., R. Mahieux, C. Pise-Masison, J. Brady, A. Gessain, S. Yamaoka and G. Franchini: Human T-cell lymphotropic virus type 1 Tax represses c-Myb-dependent transcription through activation of the NF-kappaB pathway and modulation of coactivator usage. Mol Cell Biol. 21:7391-7402, 2001.

McAllister-Lucas, L. M., N. Inohara, P. C. Lucas, J. Ruland, A. Benito, Q. Li, S. Chen, F. F. Chen, S. Yamaoka, I. M. Verma, T. W. Mak and G. Nunez: Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction. J Biol Chem. 276:30589-30597, 2001.

Lucas, P. C., M. Yonezumi, N. Inohara, L. M. McAllister-Lucas, M. E. Abazeed, F. F. Chen, S. Yamaoka, M. Seto and G. Nunez: Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J Biol Chem. 276:19012-19019, 2001.

Liu, Y., Y. Wang, M. Yamakuchi, S. Masuda, T. Tokioka, S. Yamaoka, I. Maruyama and I. Kitajima: Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax. Oncogene. 20:2514-2526, 2001.

Devin, A., Y. Lin, S. Yamaoka, Z. Li, M. Karin and Z. Liu: The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol Cell Biol. 21:3986-3994, 2001.

 

2000年

Vertegaal, A. C., H. B. Kuiperij, S. Yamaoka, G. Courtois, A. J. van der Eb and A. Zantema: Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells. Cell Signal. 12:759-768, 2000.

Smahi, A., G. Courtois, P. Vabres, S. Yamaoka, S. Heuertz, A. Munnich, A. Israel, N. S. Heiss, S. M. Klauck, P. Kioschis, S. Wiemann, A. Poustka, T. Esposito, T. Bardaro, F. Gianfrancesco, A. Ciccodicola, M. D'Urso, H. Woffendin, T. Jakins, D. Donnai, H. Stewart, S. J. Kenwrick, S. Aradhya, T. Yamagata, M. Levy, R. A. Lewis and D. L. Nelson: Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature. 405:466-472, 2000.

Poyet, J. L., S. M. Srinivasula, J. H. Lin, T. Fernandes-Alnemri, S. Yamaoka, P. N. Tsichlis and E. S. Alnemri: Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization. J Biol Chem. 275:37966-37977, 2000.

Philpott, D. J., S. Yamaoka, A. Israel and P. J. Sansonetti: Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J Immunol. 165:903-914, 2000.

Nagao, N., T. Etoh, S. Yamaoka, T. Okamoto and N. Miwa: Enhanced invasion of Tax-expressing fibroblasts into the basement membrane is repressed by phosphorylated ascorbate with simultaneous decreases in intracellular oxidative stress and NF-kappa B activation. Antioxid Redox Signal. 2:727-738, 2000.

Ariumi, Y., A. Kaida, J. Y. Lin, M. Hirota, O. Masui, S. Yamaoka, Y. Taya and K. Shimotohno: HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration. Oncogene. 19:1491-1499, 2000.

 

1999年

Kaido, T., A. Yoshikawa, S. Seto, S. Yamaoka, M. Sato, T. Ishii, K. Inoue and M. Imamura: Hepatocyte growth factor supply accelerates compensatory hypertrophy caused by portal branch ligation in normal and jaundiced rats. J Surg Res. 85:115-119, 1999.

Kaido, T., A. Yoshikawa, S. Seto, S. Yamaoka, H. Furuyama, S. Arii, Y. Takahashi and M. Imamura: Pretreatment with soluble thrombomodulin prevents intrasinusoidal coagulation and liver dysfunction following extensive hepatectomy in cirrhotic rats. Thromb Haemost. 82:1302-1306, 1999.

 

1998年

Yoshikawa, A., T. Kaido, S. Seto, S. Yamaoka, M. Sato, T. Ishii and M. Imamura: Hepatocyte growth factor promotes liver regeneration with prompt improvement of hyperbilirubinemia in hepatectomized cholestatic rats. J Surg Res. 78:54-59, 1998.

Yamaoka, S., G. Courtois, C. Bessia, S. T. Whiteside, R. Weil, F. Agou, H. E. Kirk, R. J. Kay and A. Israel: Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell. 93:1231-1240, 1998.

Seto, S., T. Kaido, S. Yamaoka, A. Yoshikawa, S. Arii, T. Nakamura, M. Niwano and M. Imamura: Hepatocyte growth factor prevents lipopolysaccharide-induced hepatic sinusoidal endothelial cell injury and intrasinusoidal fibrin deposition in rats. J Surg Res. 80:194-199, 1998.

Kaido, T., A. Yoshikawa, S. Seto, S. Yamaoka, M. Sato, T. Ishii and M. Imamura: Portal branch ligation with a continuous hepatocyte growth factor supply makes extensive hepatectomy possible in cirrhotic rats. Hepatology. 28:756-760, 1998.

Kaido, T., S. Seto, S. Yamaoka, A. Yoshikawa and M. Imamura: Perioperative continuous hepatocyte growth factor supply prevents postoperative liver failure in rats with liver cirrhosis. J Surg Res. 74:173-178, 1998.

Fassati, A., A. Bardoni, M. Sironi, D. J. Wells, N. Bresolin, G. Scarlato, M. Hatanaka, S. Yamaoka and G. Dickson: Insertion of two independent enhancers in the long terminal repeat of a self-inactivating vector results in high-titer retroviral vectors with tissue-specific expression. Hum Gene Ther. 9:2459-2468, 1998.

 

1997年

Kitajima, I., N. Hanyu, Y. Soejima, R. Hirano, S. Arahira, S. Yamaoka, R. Yamada, I. Maruyama and Y. Kaneda: Efficient transfer of synthetic ribozymes into cells using hemagglutinating virus of Japan (HVJ)-cationic liposomes. Application for ribozymes that target human t-cell leukemia virus type I tax/rex mRNA. J Biol Chem. 272:27099-27106, 1997.

Kaido, T., S. Yamaoka, S. Seto, N. Funaki, T. Kasamatsu, J. Tanaka, T. Nakamura and M. Imamura: Continuous hepatocyte growth factor supply prevents lipopolysaccharide-induced liver injury in rats. FEBS Lett. 411:378-382, 1997.

 

1996年

Yamaoka, S. B., J. T. Mellonig, R. M. Meffert, R. M. Arnold, P. V. Nummikoski and B. L. Mealey: Clinical evaluation of demineralized-unicortical-ilium-strips for guided tissue regeneration. J Periodontol. 67:803-815, 1996.

Yamaoka, S., H. Inoue, M. Sakurai, T. Sugiyama, M. Hazama, T. Yamada and M. Hatanaka: Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein. EMBO J. 15:873-887, 1996.

Kaido, T., S. Yamaoka, J. Tanaka, N. Funaki, T. Kasamatsu, S. Seto, T. Nakamura and M. Imamura: Continuous HGF supply from HGF-expressing fibroblasts transplanted into spleen prevents CCl4-induced acute liver injury in rats. Biochem Biophys Res Commun. 218:1-5, 1996.

 

1994年

Yamada, T., S. Yamaoka, T. Goto, M. Nakai, Y. Tsujimoto and M. Hatanaka: The human T-cell leukemia virus type I Tax protein induces apoptosis which is blocked by the Bcl-2 protein. J Virol. 68:3374-3379, 1994.

Inoue, H., S. Yamaoka, M. Imamura and M. Hatanaka: Suppression of the transformed phenotype in hybrids of human T-cell leukemia virus type I tax-transformed rat fibroblasts and normal human fibroblasts. Exp Cell Res. 215:68-74, 1994.

 

1992年

Yamaoka, S., T. Tobe and M. Hatanaka: Tax protein of human T-cell leukemia virus type I is required for maintenance of the transformed phenotype. Oncogene. 7:433-437, 1992.

Sakurai, M., S. Yamaoka, T. Nosaka, M. Akayama, A. Tanaka, M. Maki and M. Hatanaka: Transforming activity and the level of Tax protein: effect of one point mutation in HTLV-I tax gene. Int J Cancer. 52:323-328, 1992.

 

1990年

Tsuboi, K., S. Yamaoka, M. Maki, G. Ohshio, T. Tobe and M. Hatanaka: Soluble factors including proteinases released from damaged cells may trigger the wound healing process. Biochem Biophys Res Commun. 168:1163-1170, 1990.

Tanaka, A., C. Takahashi, S. Yamaoka, T. Nosaka, M. Maki and M. Hatanaka: Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro. Proc Natl Acad Sci U S A. 87:1071-1075, 1990.